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Crystal structure of the C-terminal globular domain of oligosaccharyltransferase (afaglb-L, O29867_ARCFU) from archaeoglobus fulgidus as a mbp fusion

Analyse Crystal structure of the C-terminal globular domain of… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
3WAI
Type
protein
Length
711 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Maltose-binding periplasmic protein, transmembrane oligosaccharyl transferase
UniProt
P0AEX9, O29867
Pockets
8 · best druggability 0.57

Structure

x-ray diffraction · 1 distinct chain · 41% helix, 21% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AMaltose-binding periplasmic protein, transmembrane oligosaccharyl transferaseprotein71141% helix, 21% strandP0AEX9, O29867

Pockets

8 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
13220.570.7642empty
22900.570.7627empty
33080.540.7529empty
42120.530.7826empty
51050.380.7520empty

Compared structures

  • 3WAI · Crystal structure of the C-terminal globular domain of oligosaccharyltransferase… · the same entry in another collection · chain A against A, TM-score 1.00
  • O29867 · AlphaFold monomer V2.0 prediction for dolichyl- phosphooligosaccharide-protein… · a predicted model of the same protein · chain A against A, TM-score 0.45

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