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Crystal structure of KAP121P

Analyse Crystal structure of KAP121P in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3W3T
Type: protein
Length: 1,025 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Importin subunit beta-3
UniProt: P32337
Pockets: 5 · best druggability 0.44

Structure

x-ray diffraction · 1 distinct chain · 76% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Importin subunit beta-3	protein	1025	76% helix, 1% strand	P32337

Pockets

5 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	165	0.44	0.75	20	empty
2	127	0.40	0.75	30	empty
3	53	0.39	0.81	14	empty
4	51	0.32	0.78	12	empty
5	61	0.28	0.74	14	empty

Compared structures

3W3T · Crystal structure of Kap121p · the same entry in another collection · chain A against A, TM-score 1.00
P32337 · AlphaFold monomer V2.0 prediction for importin subunit beta-3 (P32337) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P32337
Elsewhere: RCSB PDB 3W3T · PDBe 3W3T · UniProt P32337

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