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Structure of elastase inhibitor afuei (cyrstal form I)

Analyse Structure of elastase inhibitor afuei (cyrstal form I) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3W0D
Type: protein
Length: 136 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Elastase inhibitor afuei
UniProt: Q4WZ11
Pockets: 1 · best druggability 0.53

Structure

x-ray diffraction · 1 distinct chain · 28% helix, 29% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Elastase inhibitor afuei	protein	68	28% helix, 29% strand	Q4WZ11

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	171	0.53	0.79	29	empty

Interfaces

1 interface between chains.

A–B · 716 Å² buried · 9 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

3W0D · Structure of elastase inhibitor AFUEI (cyrstal form I) · the same entry in another collection · chain A against A, TM-score 1.00
Q4WZ11 · AlphaFold monomer V2.0 prediction for elastase inhibitor afuei (Q4WZ11) · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q4WZ11
Elsewhere: RCSB PDB 3W0D · PDBe 3W0D · UniProt Q4WZ11

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