Research workbench

Crystal structure of CRISPR-associated protein

Analyse Crystal structure of CRISPR-associated protein in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3VZI
Type: protein
Length: 427 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: CRISPR-associated protein CAS5, dvulg subtype
UniProt: B2SNP4
Pockets: 5 · best druggability 0.61

Structure

x-ray diffraction · 2 distinct chains · 21% helix, 35% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	CRISPR-associated protein CAS5, dvulg subtype	protein	214	21% helix, 35% strand	B2SNP4
B	CRISPR-associated protein CAS5, dvulg subtype	protein	213	21% helix, 35% strand	B2SNP4

Pockets

5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	127	0.61	0.85	28	empty
2	124	0.53	0.82	26	empty
3	91	0.47	0.81	29	empty
4	147	0.40	0.74	30	empty
5	100	0.36	0.74	23	empty

Interfaces

1 interface between chains.

A–B · 658 Å² buried · 7 hydrogen bonds · protein-protein

Compared structures

3VZI · Crystal Structure of CRISPR-associated Protein · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt B2SNP4
Elsewhere: RCSB PDB 3VZI · PDBe 3VZI · UniProt B2SNP4

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.