Research workbench
Structural insights into substrate and cofactor selelction by SP2771
Analyse Structural insights into substrate and cofactor selelction by SP2771 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3VZ1
- Type
- protein
- Length
- 904 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Succinate-semialdehyde dehydrogenase
- UniProt
- B1XMM6
- Pockets
- 6 · best druggability 0.83
Structure
x-ray diffraction · 1 distinct chain · 44% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Succinate-semialdehyde dehydrogenase | protein | 452 | 44% helix, 19% strand | B1XMM6 |
Pockets
6 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1192 | 0.83 | 0.84 | 131 | empty |
| 2 | 355 | 0.64 | 0.79 | 53 | empty |
| 3 | 242 | 0.59 | 0.79 | 35 | empty |
| 4 | 295 | 0.56 | 0.76 | 50 | empty |
| 5 | 275 | 0.56 | 0.77 | 42 | empty |
Interfaces
1 interface between chains.
- A–B · 2465 Ų buried · 41 hydrogen bonds · protein-protein
Compared structures
- 3VZ1 · Structural insights into substrate and cofactor selelction by sp2771 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B1XMM6
- Elsewhere: RCSB PDB 3VZ1 · PDBe 3VZ1 · UniProt B1XMM6
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