Research workbench

Crystal structure of TTC0807 complexed with lysine

Analyse Crystal structure of TTC0807 complexed with lysine in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3VVE
Type: protein
Length: 482 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Amino acid ABC transporter, binding protein
UniProt: Q72JG5
Ligands: LYS, SO4
Pockets: 4 · best druggability 0.64

Structure

x-ray diffraction · 1 distinct chain · 38% helix, 31% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Amino acid ABC transporter, binding protein	protein	241	38% helix, 31% strand	Q72JG5

Ligands and binding sites

LYS · Lysine · ligand · 2 copies · chains A, B
SO4 · Sulfate ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	488	0.64	0.76	45	empty
2	99	0.44	0.78	17	empty
3	107	0.42	0.77	18	empty
4	76	0.32	0.75	24	empty

Interfaces

1 interface between chains.

A–B · 916 Å² buried · 18 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

3VVE · Crystal structure of TTC0807 complexed with Lysine · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q72JG5
Elsewhere: RCSB PDB 3VVE · PDBe 3VVE · UniProt Q72JG5

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.