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Prostate specific antigen (psa) from stallion seminal plasma

Analyse Prostate specific antigen (psa) from stallion seminal plasma in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1GVZ
Type: protein
Length: 237 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Kallikrein-1E2
EC: 3.4.21.35
UniProt: Q6H321
Pockets: 1 · best druggability 0.41

Structure

x-ray diffraction · 1 distinct chain · 14% helix, 37% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Kallikrein-1E2 (EC 3.4.21.35)	protein	237	14% helix, 37% strand	Q6H321

Ligands and binding sites

GOL · Glycerol · additive · 3 copies · chains A
ACT · Acetate ion · additive · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	87	0.41	0.78	20	empty

Modifications

Observed in the structure: 5 disulfide (disulfide).

Compared structures

1GVZ · Prostate Specific Antigen (PSA) from stallion seminal plasma · the same entry in another collection · chain A against A, TM-score 1.00
Q6H321 · AlphaFold monomer V2.0 prediction for kallikrein-1E2 (Q6H321) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q6H321
Elsewhere: RCSB PDB 1GVZ · PDBe 1GVZ · UniProt Q6H321

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