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Crystal structure analysis of the PDZ domain derived from the tight junction regulating protein

Analyse Crystal structure analysis of the PDZ domain derived from the tight junction… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3VQF
Type: protein
Length: 85 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: E3 ubiquitin-protein ligase lnx
UniProt: O70263
Pockets: 1 · best druggability 0.35

Structure

x-ray diffraction · 1 distinct chain · 18% helix, 35% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	E3 ubiquitin-protein ligase lnx	protein	85	18% helix, 35% strand	O70263

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	69	0.35	0.76	13	empty

Compared structures

3VQF · Crystal Structure Analysis of the PDZ Domain Derived from the Tight Junction Regulating… · the same entry in another collection · chain A against A, TM-score 1.00
O70263 · AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase lnx (O70263) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O70263
Elsewhere: RCSB PDB 3VQF · PDBe 3VQF · UniProt O70263

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