Research workbench
Crystal structure of leucine dehydrogenase from a psychrophilic bacterium sporosarcina psychrophila.
Analyse Crystal structure of leucine dehydrogenase from a psychrophilic bacterium… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3VPX
- Type
- protein
- Length
- 715 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Leucine dehydrogenase
- EC
- 1.4.1.9
- UniProt
- I0IJU1
- Pockets
- 8 · best druggability 0.68
Structure
x-ray diffraction · 2 distinct chains · 43% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Leucine dehydrogenase (EC 1.4.1.9) | protein | 356 | 44% helix, 15% strand | I0IJU1 |
| B | Leucine dehydrogenase (EC 1.4.1.9) | protein | 359 | 42% helix, 15% strand | I0IJU1 |
Pockets
8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 730 | 0.68 | 0.76 | 61 | empty |
| 2 | 705 | 0.68 | 0.76 | 51 | empty |
| 3 | 368 | 0.55 | 0.74 | 46 | empty |
| 4 | 305 | 0.50 | 0.73 | 34 | empty |
| 5 | 61 | 0.39 | 0.80 | 18 | empty |
Interfaces
1 interface between chains.
- A–B · 1432 Ų buried · 29 hydrogen bonds · protein-protein
Compared structures
- 3VPX · Crystal structure of leucine dehydrogenase from a psychrophilic bacterium Sporosarcina… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt I0IJU1
- Elsewhere: RCSB PDB 3VPX · PDBe 3VPX · UniProt I0IJU1
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.