Research workbench
Structure of a putative phosphoserine aminotransferase from mycobacterium tuberculosis
Analyse Structure of a putative phosphoserine aminotransferase from mycobacterium… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3VOM
- Type
- protein
- Length
- 736 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Putative phosphoserine aminotransferase
- EC
- 2.6.1.52
- UniProt
- P63514
- Ligands
- PLP, SO4
- Pockets
- 3 · best druggability 0.76
Structure
x-ray diffraction · 1 distinct chain · 39% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Putative phosphoserine aminotransferase (EC 2.6.1.52) | protein | 368 | 39% helix, 15% strand | P63514 |
Ligands and binding sites
- PLP · Pyridoxal-5'-phosphate · ligand · 2 copies · chains A, B
- SO4 · Sulfate ion · ion · chains A, B
- GOL · Glycerol · additive · 3 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 258 | 0.76 | 0.89 | 43 | PLP, GOL |
| 2 | 246 | 0.75 | 0.89 | 43 | SO4, PLP |
| 3 | 53 | 0.24 | 0.72 | 13 | empty |
Interfaces
1 interface between chains.
- A–B · 2191 Ų buried · 25 hydrogen bonds · protein-protein
Compared structures
- 3VOM · Structure of a putative phosphoserine aminotransferase from mycobacterium tuberculosis · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P63514
- Elsewhere: RCSB PDB 3VOM · PDBe 3VOM · UniProt P63514
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