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Crystal structure of wild type marr (apo form) from E.COLI

Analyse Crystal structure of wild type marr (apo form) from E.COLI in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3VOE
Type: protein
Length: 271 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Multiple antibiotic resistance protein marr
UniProt: P27245
Pockets: 2 · best druggability 0.75

Structure

x-ray diffraction · 2 distinct chains · 66% helix, 8% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Multiple antibiotic resistance protein marr	protein	136	65% helix, 8% strand	P27245
B	Multiple antibiotic resistance protein marr	protein	135	67% helix, 8% strand	P27245

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	941	0.75	0.78	68	empty
2	224	0.61	0.81	25	empty

Interfaces

1 interface between chains.

A–B · 1996 Å² buried · 12 hydrogen bonds · protein-protein

Compared structures

3VOE · Crystal Structure of wild type MarR (apo form) from E.coli · the same entry in another collection · chain A against A, TM-score 1.00
P27245 · AlphaFold monomer V2.0 prediction for multiple antibiotic resistance protein marr (P27245) · a predicted model of the same protein · chain B against A, TM-score 0.84

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P27245
Elsewhere: RCSB PDB 3VOE · PDBe 3VOE · UniProt P27245

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