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Solution structure of alfa-L-LNA:DNA duplex

Analyse Solution structure of alfa-L-LNA:DNA duplex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
1GV6
Type
DNA
Length
20 nucleotides
Chains
2
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
5- D(*CP*(ATL)P*GP*CP*(ATL)P*(ATL)P*CP*(ATL)P* GP*C) -3; 5…

Structure

solution nmr · 2 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A5- D(*CP*(ATL)P*GP*CP*(ATL)P*(ATL)P*CP*(ATL)P* GP*C) -3dna10——
B5- D(*GP*CP*AP*GP*AP*AP*GP*CP*AP*G) -3dna10——

Interfaces

1 interface between chains.

  • A–B · 492 Ų buried · 45 hydrogen bonds · nucleic-nucleic

Modifications

Observed in the structure: 4 modified (nucleotide modification).

Compared structures

  • 1GV6 · Solution structure of alfa-L-LNA:DNA duplex · the same entry in another collection · chain A against A, TM-score 1.00

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