Research workbench

Crystal structure of yeast proteasome interacting protein

Analyse Crystal structure of yeast proteasome interacting protein in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3VLE
Type: protein
Length: 864 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: DNA mismatch repair protein HSM3
UniProt: P38348
Pockets: 6 · best druggability 0.64

Structure

x-ray diffraction · 2 distinct chains · 74% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA mismatch repair protein HSM3	protein	435	74% helix, 0% strand	P38348
B	DNA mismatch repair protein HSM3	protein	429	74% helix, 0% strand	P38348

Pockets

6 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	295	0.64	0.81	35	empty
2	275	0.62	0.80	35	empty
3	220	0.56	0.78	32	empty
4	210	0.54	0.78	28	empty
5	230	0.52	0.76	32	empty

Interfaces

1 interface between chains.

A–B · 1246 Å² buried · 10 hydrogen bonds · protein-protein

Compared structures

3VLE · Crystal structure of yeast proteasome interacting protein · the same entry in another collection · chain A against A, TM-score 1.00
P38348 · AlphaFold monomer V2.0 prediction for DNA mismatch repair protein HSM3 (P38348) · a predicted model of the same protein · chain B against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P38348
Elsewhere: RCSB PDB 3VLE · PDBe 3VLE · UniProt P38348

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.