Research workbench
Crystal structure of S. cerevisiae GET3 in the semi open conformation in complex with GET1 cytosolic domain at 4.5 ångström resolution
Analyse Crystal structure of S. cerevisiae GET3 in the semi open conformation in… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3VLC
- Type
- protein
- Length
- 367 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- ATPase GET3; Golgi to er traffic protein 1
- EC
- 3.6.-.-
- UniProt
- P53192
- Ligands
- ADP
- Pockets
- 6 · best druggability 0.48
Structure
x-ray diffraction · 2 distinct chains · 47% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | ATPase GET3 (EC 3.6.-.-) | protein | 302 | 43% helix, 15% strand | — |
| E | Golgi to er traffic protein 1 | protein | 65 | 65% helix, 0% strand | P53192 |
Ligands and binding sites
- ADP · Adenosine-5'-diphosphate · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
6 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 135 | 0.48 | 0.78 | 22 | empty |
| 2 | 196 | 0.46 | 0.74 | 25 | empty |
| 3 | 119 | 0.41 | 0.76 | 29 | ADP |
| 4 | 53 | 0.36 | 0.79 | 11 | empty |
| 5 | 70 | 0.35 | 0.76 | 12 | empty |
Interfaces
1 interface between chains.
- A–E · 608 Ų buried · 6 hydrogen bonds · protein-protein
Compared structures
- 3VLC · Crystal structure of S. cerevisiae Get3 in the semi open conformation in complex with… · the same entry in another collection · chain A against A, TM-score 1.00
- P53192 · AlphaFold monomer V2.0 prediction for golgi to er traffic protein 1 (P53192) · a predicted model of the same protein · chain E against A, TM-score 0.91
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P53192
- Elsewhere: RCSB PDB 3VLC · PDBe 3VLC · UniProt P53192
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.