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Crystal structure of yeast RPN14

Analyse Crystal structure of yeast RPN14 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3VL1
Type: protein
Length: 832 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: 26S proteasome regulatory subunit RPN14
UniProt: P53196
Pockets: 12 · best druggability 0.81

Structure

x-ray diffraction · 1 distinct chain · 2% helix, 49% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	26S proteasome regulatory subunit RPN14	protein	416	2% helix, 49% strand	P53196

Pockets

12 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	296	0.81	0.93	68	empty
2	388	0.72	0.83	47	empty
3	294	0.68	0.83	40	empty
4	433	0.64	0.77	50	empty
5	364	0.61	0.77	46	empty

Interfaces

1 interface between chains.

A–B · 2160 Å² buried · 24 hydrogen bonds · protein-protein

Compared structures

3VL1 · Crystal structure of yeast Rpn14 · the same entry in another collection · chain A against A, TM-score 1.00
P53196 · AlphaFold monomer V2.0 prediction for 26S proteasome regulatory subunit RPN14 (P53196) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P53196
Elsewhere: RCSB PDB 3VL1 · PDBe 3VL1 · UniProt P53196

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