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Crystal structure of hypothetical transcription factor nhtf from neisseria

Analyse Crystal structure of hypothetical transcription factor nhtf from neisseria in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3VK0
Type: protein
Length: 264 residues
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Transcriptional regulator
UniProt: Q7DDD9
Pockets: 5 · best druggability 0.72

Structure

x-ray diffraction · 3 distinct chains · 61% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Transcriptional regulator	protein	89	61% helix, 0% strand	Q7DDD9
B	Transcriptional regulator	protein	87	61% helix, 1% strand	Q7DDD9
C	Transcriptional regulator	protein	88	63% helix, 1% strand	Q7DDD9

Pockets

5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	55	0.72	0.98	14	empty
2	63	0.36	0.78	11	empty
3	67	0.32	0.75	15	empty
4	71	0.32	0.75	13	empty
5	50	0.26	0.73	11	empty

Interfaces

2 interfaces between chains.

B–C · 989 Å² buried · 9 hydrogen bonds · protein-protein
A–B · 841 Å² buried · 2 hydrogen bonds · protein-protein

Compared structures

3VK0 · Crystal Structure of hypothetical transcription factor NHTF from Neisseria · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q7DDD9
Elsewhere: RCSB PDB 3VK0 · PDBe 3VK0 · UniProt Q7DDD9

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