Research workbench
The insertion mutant Y61GG of tm CEL12A
Analyse The insertion mutant Y61GG of tm CEL12A in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3VHP
- Type
- protein
- Length
- 514 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Endo-1,4-beta-glucanase
- EC
- 3.2.1.4
- UniProt
- Q60032
- Ligands
- BGC
- Pockets
- 3 · best druggability 0.61
Structure
x-ray diffraction · 1 distinct chain · 9% helix, 56% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Endo-1,4-beta-glucanase (EC 3.2.1.4) | protein | 257 | 9% helix, 56% strand | Q60032 |
Ligands and binding sites
- BGC · beta-D-glucopyranose · sugar · 4 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 243 | 0.61 | 0.80 | 32 | BGC |
| 2 | 249 | 0.60 | 0.80 | 32 | BGC |
| 3 | 124 | 0.45 | 0.78 | 24 | empty |
Interfaces
1 interface between chains.
- A–B · 589 Ų buried · 5 hydrogen bonds · protein-protein
Compared structures
- 3VHP · The insertion mutant Y61GG of Tm Cel12A · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q60032
- Elsewhere: RCSB PDB 3VHP · PDBe 3VHP · UniProt Q60032
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