Research workbench
SSV1 integrase C-terminal catalytic domain (174-335AA)
Analyse SSV1 integrase C-terminal catalytic domain (174-335AA) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3VCF
- Type
- protein
- Length
- 306 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Probable integrase
- UniProt
- P20214
- Pockets
- 3 · best druggability 0.41
Structure
x-ray diffraction · 2 distinct chains · 55% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Probable integrase | protein | 160 | 53% helix, 11% strand | P20214 |
| B | Probable integrase | protein | 146 | 58% helix, 11% strand | P20214 |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 80 | 0.41 | 0.78 | 18 | empty |
| 2 | 86 | 0.36 | 0.75 | 15 | empty |
| 3 | 57 | 0.31 | 0.76 | 11 | empty |
Interfaces
1 interface between chains.
- A–B · 657 Ų buried · 12 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 3VCF · SSV1 integrase C-terminal catalytic domain (174-335aa) · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P20214
- Elsewhere: RCSB PDB 3VCF · PDBe 3VCF · UniProt P20214
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