Research workbench
Crystal structure of ciona intestinalis voltage sensor-containing phosphatase (ci-vsp), residues 241-576(C363S), deletion of 401-405
Analyse Crystal structure of ciona intestinalis voltage sensor-containing phosphatase… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3V0J
- Type
- protein
- Length
- 639 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Voltage-sensor containing phosphatase
- UniProt
- Q4W8A1
- Ligands
- PO4
- Pockets
- 4 · best druggability 0.78
Structure
x-ray diffraction · 2 distinct chains · 27% helix, 31% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Voltage-sensor containing phosphatase | protein | 319 | 27% helix, 31% strand | Q4W8A1 |
| B | Voltage-sensor containing phosphatase | protein | 320 | 27% helix, 31% strand | Q4W8A1 |
Ligands and binding sites
- PO4 · Phosphate ion · ion · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 800 | 0.78 | 0.81 | 69 | empty |
| 2 | 119 | 0.44 | 0.77 | 24 | empty |
| 3 | 122 | 0.41 | 0.76 | 27 | empty |
| 4 | 89 | 0.41 | 0.78 | 27 | empty |
Interfaces
1 interface between chains.
- A–B · 388 Ų buried · 4 hydrogen bonds · protein-protein
Compared structures
- 3V0J · Crystal structure of Ciona intestinalis voltage sensor-containing phosphatase (Ci-VSP)… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q4W8A1
- Elsewhere: RCSB PDB 3V0J · PDBe 3V0J · UniProt Q4W8A1
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.