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Crystal structure of equine serum albumin

Analyse Crystal structure of equine serum albumin in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3V08
Type: protein
Length: 581 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Serum albumin
UniProt: P35747
Ligands: UNX, BR, SO4
Pockets: 8 · best druggability 0.79

Structure

x-ray diffraction · 1 distinct chain · 76% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Serum albumin	protein	581	76% helix, 0% strand	P35747

Ligands and binding sites

UNX · Unknown atom or ion · ion · 12 copies · chains A
BR · Bromide ion · ion · 11 copies · chains A
SO4 · Sulfate ion · ion · 6 copies · chains A
EDO · 1,2-ethanediol · additive · chains A
PG4 · Tetraethylene glycol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

8 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	558	0.79	0.85	53	EDO, UNX
2	927	0.77	0.79	59	BR
3	259	0.67	0.83	39	SO4, BR
4	108	0.65	0.89	29	BR
5	305	0.59	0.77	27	empty

Modifications

Observed in the structure: 17 disulfide (disulfide).

Compared structures

3V08 · Crystal structure of Equine Serum Albumin · the same entry in another collection · chain A against A, TM-score 1.00
P35747 · AlphaFold monomer V2.0 prediction for albumin (P35747) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P35747
Elsewhere: RCSB PDB 3V08 · PDBe 3V08 · UniProt P35747

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