Research workbench
Crystal structure of spoiiiah and spoiiq complex
Analyse Crystal structure of spoiiiah and spoiiq complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3UZ0
- Type
- protein
- Length
- 513 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Stage III sporulation protein ah; Stage II sporulation protein Q
- UniProt
- P49785, P71044
- Ligands
- SO4
- Pockets
- 7 · best druggability 0.65
Structure
x-ray diffraction · 3 distinct chains · 39% helix, 28% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Stage III sporulation protein ah | protein | 114 | 59% helix, 16% strand | P49785 |
| B, D | Stage II sporulation protein Q | protein | 143 | 7% helix, 45% strand | P71044 |
| C | Stage III sporulation protein ah | protein | 113 | 59% helix, 17% strand | P49785 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · 3 copies · chains A, B, C, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
7 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 586 | 0.65 | 0.76 | 71 | empty |
| 2 | 53 | 0.49 | 0.86 | 24 | empty |
| 3 | 178 | 0.45 | 0.75 | 21 | empty |
| 4 | 80 | 0.41 | 0.79 | 21 | empty |
| 5 | 50 | 0.32 | 0.77 | 13 | empty |
Interfaces
4 interfaces between chains.
- A–B · 740 Ų buried · 11 hydrogen bonds · protein-protein
- C–D · 688 Ų buried · 9 hydrogen bonds · protein-protein
- B–D · 480 Ų buried · 4 hydrogen bonds · protein-protein
- A–D · 47 Ų buried · 0 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 10 modified (engineered).
Compared structures
- 3UZ0 · Crystal Structure of SpoIIIAH and SpoIIQ Complex · the same entry in another collection · chain A against A, TM-score 1.00
- P71044 · AlphaFold monomer V2.0 prediction for stage II sporulation protein Q (P71044) · a predicted model of the same protein · chain B against A, TM-score 0.97
- P49785 · AlphaFold monomer V2.0 prediction for stage III sporulation protein ah (P49785) · a predicted model of the same protein · chain C against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P49785
- Every structure of UniProt P71044
- Elsewhere: RCSB PDB 3UZ0 · PDBe 3UZ0 · UniProt P49785 · UniProt P71044
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.