Research workbench

Crystal structure of N-terminal first spectrin repeat of utrophin

Analyse Crystal structure of N-terminal first spectrin repeat of utrophin in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3UUM
Type: protein
Length: 245 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Utrophin
UniProt: O55147
Ligands: MG
Pockets: 3 · best druggability 0.54

Structure

x-ray diffraction · 2 distinct chains · 87% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Utrophin	protein	122	88% helix, 0% strand	O55147
B	Utrophin	protein	123	87% helix, 0% strand	O55147

Ligands and binding sites

MG · Magnesium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	301	0.54	0.75	26	empty
2	206	0.47	0.74	25	empty
3	60	0.35	0.78	14	empty

Interfaces

1 interface between chains.

A–B · 254 Å² buried · 0 hydrogen bonds · protein-protein

Compared structures

3UUM · Crystal Structure of N-terminal first spectrin repeat of utrophin · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O55147
Elsewhere: RCSB PDB 3UUM · PDBe 3UUM · UniProt O55147

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.