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Crystal structure of first N-terminal utrophin spectrin repeat

Analyse Crystal structure of first N-terminal utrophin spectrin repeat in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3UUL
Type: protein
Length: 232 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Utrophin
UniProt: O55147
Ligands: MG
Pockets: 3 · best druggability 0.51

Structure

x-ray diffraction · 2 distinct chains · 87% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Utrophin	protein	115	87% helix, 0% strand	O55147
B	Utrophin	protein	117	86% helix, 0% strand	O55147

Ligands and binding sites

MG · Magnesium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	260	0.51	0.75	27	empty
2	166	0.44	0.75	18	empty
3	97	0.42	0.78	16	empty

Interfaces

1 interface between chains.

A–B · 236 Å² buried · 1 hydrogen bond · protein-protein

Compared structures

3UUL · Crystal Structure of first N-terminal utrophin spectrin repeat · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O55147
Elsewhere: RCSB PDB 3UUL · PDBe 3UUL · UniProt O55147

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