Research workbench
The crystal structure of dehydrogenase from sinorhizobium meliloti
Analyse The crystal structure of dehydrogenase from sinorhizobium meliloti in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3UOE
- Type
- protein
- Length
- 658 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Dehydrogenase
- UniProt
- Q930Q4
- Pockets
- 4 · best druggability 0.84
Structure
x-ray diffraction · 2 distinct chains · 44% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Dehydrogenase | protein | 339 | 45% helix, 20% strand | Q930Q4 |
| B | Dehydrogenase | protein | 319 | 43% helix, 20% strand | Q930Q4 |
Pockets
4 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 178 | 0.84 | 0.97 | 28 | empty |
| 2 | 462 | 0.68 | 0.79 | 53 | empty |
| 3 | 372 | 0.64 | 0.79 | 37 | empty |
| 4 | 186 | 0.51 | 0.77 | 41 | empty |
Interfaces
1 interface between chains.
- A–B · 3163 Ų buried · 44 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 19 modified (engineered).
Compared structures
- 3UOE · The crystal structure of dehydrogenase from Sinorhizobium meliloti · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q930Q4
- Elsewhere: RCSB PDB 3UOE · PDBe 3UOE · UniProt Q930Q4
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.