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C. elegans major sperm protein

Analyse C. elegans major sperm protein in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1GRW
Type: protein
Length: 496 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Major sperm protein 31/40/142
UniProt: P53017
Pockets: 6 · best druggability 0.51

Structure

x-ray diffraction · 1 distinct chain · 6% helix, 47% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C, D	Major sperm protein 31/40/142	protein	124	6% helix, 47% strand	P53017

Pockets

6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	117	0.51	0.81	19	empty
2	128	0.50	0.80	19	empty
3	130	0.38	0.73	24	empty
4	74	0.35	0.76	22	empty
5	83	0.32	0.73	21	empty

Interfaces

3 interfaces between chains.

A–B · 662 Å² buried · 12 hydrogen bonds · protein-protein
B–C · 651 Å² buried · 13 hydrogen bonds · protein-protein
C–D · 645 Å² buried · 10 hydrogen bonds · protein-protein

Compared structures

1GRW · C. elegans major sperm protein · the same entry in another collection · chain A against A, TM-score 1.00
P53017 · AlphaFold monomer V2.0 prediction for major sperm protein… · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P53017
Elsewhere: RCSB PDB 1GRW · PDBe 1GRW · UniProt P53017

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