Research workbench
Structure of the C-LINKER/CNBHD of zelk channels in P1 21 1 space group
Analyse Structure of the C-LINKER/CNBHD of zelk channels in P1 21 1 space group in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3UKT
- Type
- protein
- Length
- 767 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Novel protein similar to vertebrate potassium voltage-gated channel, subfamily H…
- UniProt
- A8WHX9
- Pockets
- 7 · best druggability 0.84
Structure
x-ray diffraction · 3 distinct chains · 39% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B | Novel protein similar to vertebrate potassium voltage-gated channel, subfamily H (eag-related) family | protein | 198 | 40% helix, 23% strand | A8WHX9 |
| A, C | Novel protein similar to vertebrate potassium voltage-gated channel, subfamily H (eag-related) family | protein | 196 | 41% helix, 24% strand | A8WHX9 |
| D | Novel protein similar to vertebrate potassium voltage-gated channel, subfamily H (eag-related) family | protein | 177 | 36% helix, 25% strand | A8WHX9 |
Pockets
7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1175 | 0.84 | 0.85 | 114 | empty |
| 2 | 1007 | 0.80 | 0.81 | 101 | empty |
| 3 | 127 | 0.56 | 0.83 | 23 | empty |
| 4 | 151 | 0.46 | 0.76 | 27 | empty |
| 5 | 88 | 0.40 | 0.78 | 18 | empty |
Interfaces
4 interfaces between chains.
- B–A · 1373 Ų buried · 10 hydrogen bonds · protein-protein
- C–D · 1179 Ų buried · 5 hydrogen bonds · protein-protein
- A–C · 393 Ų buried · 3 hydrogen bonds · protein-protein
- B–C · 310 Ų buried · 3 hydrogen bonds · protein-protein
Compared structures
- 3UKT · Structure of the C-linker/CNBHD of zELK channels in P1 21 1 space group · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A8WHX9
- Elsewhere: RCSB PDB 3UKT · PDBe 3UKT · UniProt A8WHX9
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