Research workbench
The crystal structure of a possible phosphate ACETYL/BUTARYL transferase (from listeria monocytogenes egd-E) in complex with cod (3'-dephosphocoenzyme a)
Analyse The crystal structure of a possible phosphate ACETYL/BUTARYL transferase (from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3UF6
- Type
- protein
- Length
- 571 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- LMO1369 protein
- UniProt
- Q8Y7B7
- Ligands
- COD
- Pockets
- 6 · best druggability 0.68
Structure
x-ray diffraction · 2 distinct chains · 38% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | LMO1369 protein | protein | 285 | 39% helix, 18% strand | Q8Y7B7 |
| B | LMO1369 protein | protein | 286 | 38% helix, 18% strand | Q8Y7B7 |
Ligands and binding sites
- COD · Dephospho coenzyme A · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 386 | 0.68 | 0.81 | 42 | empty |
| 2 | 399 | 0.68 | 0.80 | 41 | COD |
| 3 | 173 | 0.51 | 0.78 | 26 | empty |
| 4 | 62 | 0.33 | 0.76 | 13 | empty |
| 5 | 57 | 0.31 | 0.76 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 1544 Ų buried · 15 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 6 modified (engineered).
Compared structures
- 3UF6 · The crystal structure of a possible phosphate acetyl/butaryl transferase (from Listeria… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8Y7B7
- Elsewhere: RCSB PDB 3UF6 · PDBe 3UF6 · UniProt Q8Y7B7
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.