Research workbench
Crystal structure of a small-chain dehydrogenase
Analyse Crystal structure of a small-chain dehydrogenase in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3UCF
- Type
- protein
- Length
- 776 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Dehydrogenase
- UniProt
- Q7MBY8
- Pockets
- 5 · best druggability 0.81
Structure
x-ray diffraction · 4 distinct chains · 46% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Dehydrogenase | protein | 187 | 48% helix, 22% strand | Q7MBY8 |
| B | Dehydrogenase | protein | 195 | 46% helix, 21% strand | Q7MBY8 |
| C | Dehydrogenase | protein | 208 | 46% helix, 21% strand | Q7MBY8 |
| D | Dehydrogenase | protein | 186 | 46% helix, 21% strand | Q7MBY8 |
Pockets
5 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1192 | 0.81 | 0.82 | 92 | empty |
| 2 | 330 | 0.58 | 0.77 | 49 | empty |
| 3 | 227 | 0.52 | 0.76 | 38 | empty |
| 4 | 219 | 0.51 | 0.76 | 34 | empty |
| 5 | 195 | 0.48 | 0.75 | 34 | empty |
Interfaces
6 interfaces between chains.
- B–D · 1577 Ų buried · 11 hydrogen bonds · protein-protein
- A–C · 1566 Ų buried · 10 hydrogen bonds · protein-protein
- A–B · 1280 Ų buried · 14 hydrogen bonds · protein-protein
- C–D · 1209 Ų buried · 8 hydrogen bonds · protein-protein
- B–C · 105 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 3UCF · Crystal structure of a small-chain dehydrogenase · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q7MBY8
- Elsewhere: RCSB PDB 3UCF · PDBe 3UCF · UniProt Q7MBY8
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.