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N-terminal domain of bombyx mori fibroin mediates the assembly of silk in response to pH decrease

Analyse N-terminal domain of bombyx mori fibroin mediates the assembly of silk in… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3UA0
Type: protein
Length: 149 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Fibroin heavy chain
UniProt: P05790
Pockets: 3 · best druggability 0.43

Structure

x-ray diffraction · 2 distinct chains · 3% helix, 59% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Fibroin heavy chain	protein	79	0% helix, 57% strand	P05790
B	Fibroin heavy chain	protein	70	6% helix, 61% strand	P05790

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	75	0.43	0.80	17	empty
2	83	0.37	0.76	13	empty
3	59	0.28	0.74	18	empty

Interfaces

1 interface between chains.

A–B · 2393 Å² buried · 58 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 6 modified (engineered).

Compared structures

3UA0 · N-Terminal Domain of Bombyx mori Fibroin Mediates the Assembly of Silk in Response to pH… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P05790
Elsewhere: RCSB PDB 3UA0 · PDBe 3UA0 · UniProt P05790

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