Research workbench
Crystal structure of the F177S mutant of mycrocine immunity protein (mccf) with AMP
Analyse Crystal structure of the F177S mutant of mycrocine immunity protein (mccf) with… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3TYX
- Type
- protein
- Length
- 667 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Microcin immunity protein mccf
- UniProt
- Q81RT8
- Ligands
- AMP
- Pockets
- 4 · best druggability 0.60
Structure
x-ray diffraction · 2 distinct chains · 31% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Microcin immunity protein mccf | protein | 335 | 30% helix, 22% strand | Q81RT8 |
| B | Microcin immunity protein mccf | protein | 332 | 31% helix, 23% strand | Q81RT8 |
Ligands and binding sites
- AMP · Adenosine monophosphate · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 349 | 0.60 | 0.77 | 48 | AMP |
| 2 | 226 | 0.51 | 0.76 | 35 | AMP |
| 3 | 102 | 0.41 | 0.76 | 18 | empty |
| 4 | 60 | 0.34 | 0.77 | 20 | empty |
Interfaces
1 interface between chains.
- A–B · 1806 Ų buried · 45 hydrogen bonds · protein-protein
Compared structures
- 3TYX · Crystal structure of the F177S mutant of mycrocine immunity protein (MccF) with AMP · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q81RT8
- Elsewhere: RCSB PDB 3TYX · PDBe 3TYX · UniProt Q81RT8
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