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Crystal structure of RPN6 from drosophila melanogaster, GD(3+) complex

Analyse Crystal structure of RPN6 from drosophila melanogaster, GD(3+) complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3TXM
Type: protein
Length: 353 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: 26S proteasome regulatory complex subunit P42B
UniProt: Q7KLV9
Ligands: GD3, SO4
Pockets: 1 · best druggability 0.55

Structure

x-ray diffraction · 1 distinct chain · 75% helix, 3% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	26S proteasome regulatory complex subunit P42B	protein	353	75% helix, 3% strand	Q7KLV9

Ligands and binding sites

GD3 · Gadolinium ion · metal · 4 copies · chains A
SO4 · Sulfate ion · ion · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	299	0.55	0.75	40	empty

Compared structures

3TXM · Crystal structure of Rpn6 from Drosophila melanogaster, Gd(3+) complex · the same entry in another collection · chain A against A, TM-score 1.00
Q7KLV9 · AlphaFold monomer V2.0 prediction for 26S proteasome non-ATPase regulatory subunit 11… · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q7KLV9
Elsewhere: RCSB PDB 3TXM · PDBe 3TXM · UniProt Q7KLV9

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