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Structural basis for the altered T-cell receptor binding specificty in a superantigenic staphylococcus aureus enterotoxin-B mutant

Analyse Structural basis for the altered T-cell receptor binding specificty in a… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1GOZ
Type: protein
Length: 456 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Enterotoxin type B
UniProt: P01552
Pockets: 3 · best druggability 0.71

Structure

x-ray diffraction · 1 distinct chain · 18% helix, 42% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Enterotoxin type B	protein	228	18% helix, 42% strand	P01552

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	719	0.71	0.78	63	empty
2	310	0.62	0.80	45	empty
3	62	0.28	0.73	13	empty

Interfaces

1 interface between chains.

A–B · 808 Å² buried · 7 hydrogen bonds · protein-protein

Compared structures

1GOZ · Structural basis for the altered T-cell receptor binding specificty in a superantigenic… · the same entry in another collection · chain A against A, TM-score 1.00
P01552 · AlphaFold monomer V2.0 prediction for enterotoxin type B (P01552) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P01552
Elsewhere: RCSB PDB 1GOZ · PDBe 1GOZ · UniProt P01552

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