Research workbench
Crystal structure of GCN5-related N-acetyltransferase from sphaerobacter thermophilus
Analyse Crystal structure of GCN5-related N-acetyltransferase from sphaerobacter… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3TT2
- Type
- protein
- Length
- 315 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- GCN5-related N-acetyltransferase
- UniProt
- D1C2H7
- Ligands
- SO4
- Pockets
- 3 · best druggability 0.76
Structure
x-ray diffraction · 1 distinct chain · 33% helix, 32% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | GCN5-related N-acetyltransferase | protein | 315 | 33% helix, 32% strand | D1C2H7 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · 6 copies · chains A
- GOL · Glycerol · additive · 5 copies · chains A
- MES · 2-(N-morpholino)-ethanesulfonic acid · additive · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 679 | 0.76 | 0.81 | 58 | GOL, SO4, MES |
| 2 | 140 | 0.47 | 0.77 | 20 | empty |
| 3 | 92 | 0.34 | 0.74 | 24 | SO4 |
Modifications
Observed in the structure: 6 modified (engineered).
Compared structures
- 3TT2 · Crystal Structure of GCN5-related N-Acetyltransferase from Sphaerobacter thermophilus · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt D1C2H7
- Elsewhere: RCSB PDB 3TT2 · PDBe 3TT2 · UniProt D1C2H7
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