Research workbench

Spinosyn rhamnosyltransferase spng

Analyse Spinosyn rhamnosyltransferase spng in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3TSA
Type: protein
Length: 744 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ndp-rhamnosyltransferase
EC: 2.4.1.-
UniProt: Q9ALM8
Ligands: GLC, MG
Pockets: 7 · best druggability 0.79

Structure

x-ray diffraction · 2 distinct chains · 48% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ndp-rhamnosyltransferase (EC 2.4.1.-)	protein	372	48% helix, 16% strand	Q9ALM8
B	Ndp-rhamnosyltransferase (EC 2.4.1.-)	protein	372	48% helix, 16% strand	Q9ALM8

Ligands and binding sites

GLC · alpha-D-glucopyranose · sugar · chains B
MG · Magnesium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

7 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	746	0.79	0.83	72	empty
2	579	0.79	0.84	62	empty
3	172	0.69	0.88	35	empty
4	153	0.68	0.88	34	empty
5	85	0.44	0.80	19	empty

Interfaces

1 interface between chains.

A–B · 1299 Å² buried · 19 hydrogen bonds · protein-protein

Compared structures

3TSA · Spinosyn Rhamnosyltransferase SpnG · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9ALM8
Elsewhere: RCSB PDB 3TSA · PDBe 3TSA · UniProt Q9ALM8

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.