Research workbench
Structure of an enolase (eno) from coxiella burnetii
Analyse Structure of an enolase (eno) from coxiella burnetii in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3TQP
- Type
- protein
- Length
- 822 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Enolase
- EC
- 4.2.1.11
- UniProt
- Q83B44
- Ligands
- MG, PO4
- Pockets
- 8 · best druggability 0.75
Structure
x-ray diffraction · 2 distinct chains · 42% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Enolase (EC 4.2.1.11) | protein | 418 | 41% helix, 18% strand | Q83B44 |
| B | Enolase (EC 4.2.1.11) | protein | 404 | 43% helix, 17% strand | Q83B44 |
Ligands and binding sites
- MG · Magnesium ion · metal · 2 copies · chains A, B
- PO4 · Phosphate ion · ion · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1197 | 0.75 | 0.78 | 66 | empty |
| 2 | 381 | 0.67 | 0.81 | 59 | PO4, MG |
| 3 | 243 | 0.53 | 0.77 | 43 | PO4, MG |
| 4 | 118 | 0.48 | 0.79 | 19 | empty |
| 5 | 78 | 0.31 | 0.73 | 21 | empty |
Interfaces
1 interface between chains.
- A–B · 1648 Ų buried · 26 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 14 modified (engineered).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q83B44
- Elsewhere: RCSB PDB 3TQP · PDBe 3TQP · UniProt Q83B44
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