Research workbench
Microcin C7 self immunity protein mccf in the inactive mutant apo state
Analyse Microcin C7 self immunity protein mccf in the inactive mutant apo state in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3TLG
- Type
- protein
- Length
- 668 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Mccf
- UniProt
- Q2KKH9
- Pockets
- 4 · best druggability 0.68
Structure
x-ray diffraction · 2 distinct chains · 31% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Mccf | protein | 333 | 32% helix, 23% strand | Q2KKH9 |
| B | Mccf | protein | 335 | 31% helix, 23% strand | Q2KKH9 |
Pockets
4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 670 | 0.68 | 0.77 | 82 | empty |
| 2 | 170 | 0.54 | 0.79 | 24 | empty |
| 3 | 96 | 0.53 | 0.83 | 25 | empty |
| 4 | 53 | 0.30 | 0.76 | 11 | empty |
Interfaces
1 interface between chains.
- A–B · 1872 Ų buried · 47 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 7 modified (engineered).
Compared structures
- 3TLG · Microcin C7 self immunity protein MccF in the inactive mutant APO state · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q2KKH9
- Elsewhere: RCSB PDB 3TLG · PDBe 3TLG · UniProt Q2KKH9
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