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Crystal structure of quasiracemic villin headpiece subdomain containing (F5PHE10) substitution

Analyse Crystal structure of quasiracemic villin headpiece subdomain containing… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3TJW
Type: protein
Length: 68 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: D-villin-1; L-villin-1
UniProt: P02640
Ligands: SO4

Structure

x-ray diffraction · 2 distinct chains · 71% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	D-villin-1	protein	34	71% helix, 0% strand	P02640
B	L-villin-1	protein	34	71% helix, 0% strand	P02640

Ligands and binding sites

SO4 · Sulfate ion · ion · 3 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

A–B · 266 Å² buried · 3 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 32 d-amino, 1 modified (D-amino acid, nonstandard).

Compared structures

3TJW · Crystal Structure of Quasiracemic Villin Headpiece Subdomain Containing (F5Phe10)… · the same entry in another collection · chain A against A, TM-score 1.00
P02640 · AlphaFold monomer V2.0 prediction for villin-1 (P02640) · a predicted model of the same protein · chain B against A, TM-score 0.92

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P02640
Elsewhere: RCSB PDB 3TJW · PDBe 3TJW · UniProt P02640

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