Research workbench
Crystal structure of HUTZ,THE heme storsge protein from vibrio cholerae
Analyse Crystal structure of HUTZ,THE heme storsge protein from vibrio cholerae in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3TGV
- Type
- protein
- Length
- 568 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Heme-binding protein hutz
- UniProt
- A5F0R4
- Ligands
- BEZ
- Pockets
- 9 · best druggability 0.61
Structure
x-ray diffraction · 1 distinct chain · 33% helix, 38% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D | Heme-binding protein hutz | protein | 142 | 33% helix, 38% strand | A5F0R4 |
Ligands and binding sites
- BEZ · Benzoic acid · ligand · 4 copies · chains B, C, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
9 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 210 | 0.61 | 0.82 | 31 | empty |
| 2 | 236 | 0.60 | 0.80 | 32 | empty |
| 3 | 230 | 0.58 | 0.79 | 30 | empty |
| 4 | 248 | 0.58 | 0.79 | 30 | empty |
| 5 | 229 | 0.57 | 0.79 | 26 | empty |
Interfaces
3 interfaces between chains.
- C–D · 1684 Ų buried · 25 hydrogen bonds · protein-protein
- A–B · 1665 Ų buried · 26 hydrogen bonds · protein-protein
- B–D · 648 Ų buried · 4 hydrogen bonds · protein-protein
Compared structures
- 3TGV · Crystal structure of HutZ,the heme storsge protein from Vibrio cholerae · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A5F0R4
- Elsewhere: RCSB PDB 3TGV · PDBe 3TGV · UniProt A5F0R4
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