Research workbench
Guanine nucleotide dissociation inhibitor, alpha-isoform
Analyse Guanine nucleotide dissociation inhibitor, alpha-isoform in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1GND
- Type
- protein
- Length
- 430 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Guanine nucleotide dissociation inhibitor
- UniProt
- P21856
- Pockets
- 5 · best druggability 0.59
Structure
x-ray diffraction · 1 distinct chain · 35% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Guanine nucleotide dissociation inhibitor | protein | 430 | 35% helix, 24% strand | P21856 |
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 189 | 0.59 | 0.81 | 23 | empty |
| 2 | 103 | 0.53 | 0.84 | 27 | empty |
| 3 | 140 | 0.43 | 0.76 | 25 | empty |
| 4 | 91 | 0.39 | 0.77 | 17 | empty |
| 5 | 66 | 0.33 | 0.76 | 19 | empty |
Compared structures
- 1GND · Guanine nucleotide dissociation inhibitor, alpha-isoform · the same entry in another collection · chain A against A, TM-score 1.00
- P21856 · AlphaFold monomer V2.0 prediction for rab GDP dissociation inhibitor alpha (P21856) · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P21856
- Elsewhere: RCSB PDB 1GND · PDBe 1GND · UniProt P21856
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