Research workbench
PCID2:DSS1 structure
Analyse PCID2:DSS1 structure in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3T5X
- Type
- protein
- Length
- 225 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Pci domain-containing protein 2; 26S proteasome complex subunit DSS1
- UniProt
- Q5JVF3, P60896
- Pockets
- 3 · best druggability 0.48
Structure
x-ray diffraction · 2 distinct chains · 65% helix, 7% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Pci domain-containing protein 2 | protein | 195 | 68% helix, 7% strand | Q5JVF3 |
| B | 26S proteasome complex subunit DSS1 | protein | 30 | 50% helix, 7% strand | P60896 |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 140 | 0.48 | 0.78 | 26 | empty |
| 2 | 100 | 0.45 | 0.78 | 14 | empty |
| 3 | 51 | 0.31 | 0.76 | 13 | empty |
Interfaces
1 interface between chains.
- A–B · 1299 Ų buried · 15 hydrogen bonds · protein-protein
Compared structures
- 3T5X · PCID2:DSS1 Structure · the same entry in another collection · chain A against A, TM-score 1.00
- Q5JVF3 · AlphaFold monomer V2.0 prediction for pci domain-containing protein 2 (Q5JVF3) · a predicted model of the same protein · chain A against A, TM-score 0.99
- P60896 · AlphaFold monomer V2.0 prediction for 26S proteasome complex subunit SEM1 (P60896) · a predicted model of the same protein · chain B against A, TM-score 0.48
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5JVF3
- Every structure of UniProt P60896
- Elsewhere: RCSB PDB 3T5X · PDBe 3T5X · UniProt Q5JVF3 · UniProt P60896
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