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Short chain DEHYDROGENASE/REDUCTASE family oxidoreductase from bacillus anthracis str. ames ancestor

Analyse Short chain DEHYDROGENASE/REDUCTASE family oxidoreductase from bacillus… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3T4X
Type: protein
Length: 530 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Oxidoreductase, short chain DEHYDROGENASE/REDUCTASE family
UniProt: Q81MX9
Pockets: 5 · best druggability 0.73

Structure

x-ray diffraction · 1 distinct chain · 47% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Oxidoreductase, short chain DEHYDROGENASE/REDUCTASE family	protein	265	47% helix, 16% strand	Q81MX9

Pockets

5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	568	0.73	0.80	52	empty
2	544	0.69	0.79	55	empty
3	420	0.60	0.76	38	empty
4	55	0.28	0.74	16	empty
5	61	0.27	0.73	17	empty

Interfaces

1 interface between chains.

A–B · 1620 Å² buried · 13 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 20 modified (engineered).

Compared structures

3T4X · Short chain dehydrogenase/reductase family oxidoreductase from Bacillus anthracis str.… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q81MX9
Elsewhere: RCSB PDB 3T4X · PDBe 3T4X · UniProt Q81MX9

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