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Crystal structure of modified nucleotide-free human mxa

Analyse Crystal structure of modified nucleotide-free human mxa in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
3SZR
Type
protein
Length
559 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Interferon-induced GTP-binding protein MX1
UniProt
P20591
Pockets
9 · best druggability 0.71

Structure

x-ray diffraction · 1 distinct chain · 58% helix, 7% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AInterferon-induced GTP-binding protein MX1protein55958% helix, 7% strandP20591

Pockets

9 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
14540.710.8160empty
22120.690.8633empty
31310.570.8332empty
42010.480.7534empty
51520.460.7625empty

Compared structures

  • 3SZR · Crystal structure of modified nucleotide-free human MxA · the same entry in another collection · chain A against A, TM-score 1.00
  • P20591 · AlphaFold monomer V2.0 prediction for interferon-induced GTP-binding protein MX1 (P20591) · a predicted model of the same protein · chain A against A, TM-score 0.78

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