Research workbench
Sex-lethal RNA recognition domains 1 and 2 from drosophila melanogaster
Analyse Sex-lethal RNA recognition domains 1 and 2 from drosophila melanogaster in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3SXL
- Type
- protein
- Length
- 471 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein (sex-lethal)
- UniProt
- P19339
- Pockets
- 4 · best druggability 0.52
Structure
x-ray diffraction · 1 distinct chain · 27% helix, 33% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C | Protein (sex-lethal) | protein | 157 | 27% helix, 33% strand | P19339 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 113 | 0.52 | 0.82 | 16 | empty |
| 2 | 125 | 0.50 | 0.80 | 18 | empty |
| 3 | 78 | 0.34 | 0.75 | 17 | empty |
| 4 | 72 | 0.34 | 0.75 | 16 | empty |
Interfaces
2 interfaces between chains.
- A–B · 547 Ų buried · 8 hydrogen bonds · protein-protein
- B–C · 545 Ų buried · 8 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 9 modified (engineered).
Compared structures
- 3SXL · Sex-lethal RNA recognition domains 1 and 2 from drosophila melanogaster · the same entry in another collection · chain A against A, TM-score 1.00
- P19339 · AlphaFold monomer V2.0 prediction for protein sex-lethal (P19339) · a predicted model of the same protein · chain A against A, TM-score 0.64
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P19339
- Elsewhere: RCSB PDB 3SXL · PDBe 3SXL · UniProt P19339
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