Research workbench
Structure of a short-chain type DEHYDROGENASE/REDUCTASE from mycobacterium ulcerans
Analyse Structure of a short-chain type DEHYDROGENASE/REDUCTASE from mycobacterium… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3SVT
- Type
- protein
- Length
- 549 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Short-chain type DEHYDROGENASE/REDUCTASE
- EC
- 1.-.-.-
- UniProt
- A0PUS8
- Ligands
- NA, CL
- Pockets
- 7 · best druggability 0.71
Structure
x-ray diffraction · 2 distinct chains · 52% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Short-chain type DEHYDROGENASE/REDUCTASE (EC 1.-.-.-) | protein | 274 | 52% helix, 15% strand | A0PUS8 |
| B | Short-chain type DEHYDROGENASE/REDUCTASE (EC 1.-.-.-) | protein | 275 | 53% helix, 16% strand | A0PUS8 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 492 | 0.71 | 0.80 | 48 | CL |
| 2 | 498 | 0.68 | 0.78 | 52 | empty |
| 3 | 136 | 0.43 | 0.75 | 15 | empty |
| 4 | 88 | 0.38 | 0.77 | 15 | empty |
| 5 | 76 | 0.36 | 0.77 | 16 | empty |
Interfaces
1 interface between chains.
- A–B · 1625 Ų buried · 21 hydrogen bonds · protein-protein
Compared structures
- 3SVT · Structure of a short-chain type dehydrogenase/reductase from Mycobacterium ulcerans · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0PUS8
- Elsewhere: RCSB PDB 3SVT · PDBe 3SVT · UniProt A0PUS8
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