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Crystal structure of the W180A mutant of microcin immunity protein mccf from bacillus anthracis shows the active site loop in the open conformation.

Analyse Crystal structure of the W180A mutant of microcin immunity protein mccf from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3SR3
Type: protein
Length: 637 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Microcin immunity protein mccf
UniProt: Q81RT8
Pockets: 3 · best druggability 0.54

Structure

x-ray diffraction · 2 distinct chains · 32% helix, 24% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Microcin immunity protein mccf	protein	333	31% helix, 25% strand	Q81RT8
B	Microcin immunity protein mccf	protein	304	34% helix, 23% strand	Q81RT8

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	302	0.54	0.75	36	empty
2	160	0.46	0.76	27	empty
3	93	0.40	0.77	18	empty

Interfaces

1 interface between chains.

A–B · 1826 Å² buried · 42 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

3SR3 · Crystal structure of the w180a mutant of microcin immunity protein mccf from Bacillus… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q81RT8
Elsewhere: RCSB PDB 3SR3 · PDBe 3SR3 · UniProt Q81RT8

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