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Crystal structure of an immunoglobulin I-set domain of LRIG3 protein (LRIG3) from mus musculus at 1.70 a resolution

Analyse Crystal structure of an immunoglobulin I-set domain of LRIG3 protein (LRIG3)… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
3SO5
Type
protein
Length
217 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Leucine-rich repeats and immunoglobulin-like domains protein 3
UniProt
Q6P1C6
Ligands
CL, SO4

Structure

x-ray diffraction · 2 distinct chains · 6% helix, 53% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ALeucine-rich repeats and immunoglobulin-like domains protein 3protein1056% helix, 55% strandQ6P1C6
BLeucine-rich repeats and immunoglobulin-like domains protein 3protein1125% helix, 52% strandQ6P1C6

Ligands and binding sites

  • CL · Chloride ion · ion · 4 copies · chains A, B
  • SO4 · Sulfate ion · ion · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

  • A–B · 729 Ų buried · 7 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 21 modified (methylation, engineered, nonstandard).

Compared structures

  • 3SO5 · Crystal structure of an Immunoglobulin I-set domain of Lrig3 protein (Lrig3) from MUS… · the same entry in another collection · chain A against A, TM-score 1.00
  • Q6P1C6 · AlphaFold monomer V2.0 prediction for leucine-rich repeats and immunoglobulin-like… · a predicted model of the same protein · chain A against A, TM-score 0.93

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