X-ray structure of fully glycosylated bifunctional nuclease TBN1 from solanum lycopersicum (tomato)

Structure

x-ray diffraction · 1 distinct chain · 62% helix, 5% strand (DSSP).

Ligands and binding sites

• NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 6 copies · chains A
• BMA · beta-D-mannopyranose · sugar · 3 copies · chains A
• MAN · alpha-D-mannopyranose · sugar · chains A
• ZN · Zinc ion · metal · 3 copies · chains A
• SO4 · Sulfate ion · ion · chains A
• CL · Chloride ion · ion · chains A
• BTB · 2-[bis-(2-hydroxy-ethyl)-amino]-2-hydroxymethyl-propane-1,3-diol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Modifications

Observed in the structure: 3 disulfide, 3 glycan (disulfide, N-glycosylation).

Compared structures

• 3SNG · X-ray structure of fully glycosylated bifunctional nuclease TBN1 from Solanum… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q0KFV0
• Elsewhere: RCSB PDB 3SNG · PDBe 3SNG · UniProt Q0KFV0