Research workbench
Crystal structure of phenazine resistance protein ehpr from enterobacter agglomerans (erwinia herbicola, pantoea agglomerans) EH1087, apo form
Analyse Crystal structure of phenazine resistance protein ehpr from enterobacter… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3SK1
- Type
- protein
- Length
- 492 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ehpr
- UniProt
- Q8GPH6
- Pockets
- 3 · best druggability 0.73
Structure
x-ray diffraction · 3 distinct chains · 20% helix, 36% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ehpr | protein | 122 | 20% helix, 38% strand | Q8GPH6 |
| B | Ehpr | protein | 122 | 20% helix, 36% strand | Q8GPH6 |
| C, D | Ehpr | protein | 124 | 20% helix, 35% strand | Q8GPH6 |
Pockets
3 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 815 | 0.73 | 0.78 | 89 | empty |
| 2 | 61 | 0.71 | 0.98 | 24 | empty |
| 3 | 54 | 0.70 | 0.98 | 23 | empty |
Interfaces
6 interfaces between chains.
- C–D · 2171 Ų buried · 29 hydrogen bonds · protein-protein
- A–B · 2108 Ų buried · 27 hydrogen bonds · protein-protein
- A–C · 78 Ų buried · 1 hydrogen bond · protein-protein
- A–D · 61 Ų buried · 0 hydrogen bonds · protein-protein
- B–C · 46 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 3SK1 · Crystal structure of phenazine resistance protein EhpR from Enterobacter agglomerans… · the same entry in another collection · chain D against D, TM-score 1.00
- Q8GPH6 · AlphaFold monomer V2.0 prediction for phenazine antibiotic resistance protein ehpr… · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8GPH6
- Elsewhere: RCSB PDB 3SK1 · PDBe 3SK1 · UniProt Q8GPH6
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.