Research workbench
Crystal structure of a putative triosephosphate isomerase from coccidioides immitis
Analyse Crystal structure of a putative triosephosphate isomerase from coccidioides… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3S6D
- Type
- protein
- Length
- 270 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Putative triosephosphate isomerase
- EC
- 5.3.1.1
- UniProt
- P0CL22
- Ligands
- NA
- Pockets
- 4 · best druggability 0.55
Structure
x-ray diffraction · 1 distinct chain · 46% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Putative triosephosphate isomerase (EC 5.3.1.1) | protein | 270 | 46% helix, 16% strand | P0CL22 |
Ligands and binding sites
- NA · Sodium ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 147 | 0.55 | 0.82 | 31 | empty |
| 2 | 64 | 0.45 | 0.82 | 17 | empty |
| 3 | 99 | 0.41 | 0.77 | 19 | NA |
| 4 | 58 | 0.30 | 0.75 | 17 | empty |
Compared structures
- 3S6D · Crystal structure of a putative triosephosphate isomerase from Coccidioides immitis · the same entry in another collection · chain A against A, TM-score 1.00
- P0CL22 · AlphaFold monomer V2.0 prediction for putative triosephosphate isomerase (P0CL22) · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0CL22
- Elsewhere: RCSB PDB 3S6D · PDBe 3S6D · UniProt P0CL22
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