Research workbench
Lactose phosphorylase in a ternary complex with cellobiose and sulfate
Analyse Lactose phosphorylase in a ternary complex with cellobiose and sulfate in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3S4D
- Type
- protein
- Length
- 822 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Lactose phosphorylase
- EC
- 2.4.1.20
- UniProt
- Q7WTR6
- Ligands
- BGC, SO4
- Pockets
- 7 · best druggability 0.72
Structure
x-ray diffraction · 1 distinct chain · 28% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Lactose phosphorylase (EC 2.4.1.20) | protein | 822 | 28% helix, 26% strand | Q7WTR6 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 400 | 0.72 | 0.83 | 50 | empty |
| 2 | 321 | 0.69 | 0.83 | 44 | BGC, SO4 |
| 3 | 120 | 0.58 | 0.85 | 36 | empty |
| 4 | 63 | 0.47 | 0.84 | 20 | empty |
| 5 | 80 | 0.46 | 0.82 | 17 | empty |
Compared structures
- 3S4D · Lactose phosphorylase in a ternary complex with cellobiose and sulfate · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q7WTR6
- Elsewhere: RCSB PDB 3S4D · PDBe 3S4D · UniProt Q7WTR6
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